Peptide and Protein Bioanalysis Boot Camp

Building Proficiency in LC-MS Large Molecule Quantification

Peptide and Protein Bioanalysis Boot Camp

Waters’ team of bioanalysis experts developed the Peptide & Protein Bioanalysis Boot Camp – a series of short, recorded presentations – to help you and your colleagues acquire a fundamental and practical proficiency in large molecule quantification.

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Integrated Microflow LC-MS for Peptide & Protein Quantification

In this module, Waters' Market Development Manager, Logan Umberger explains how to apply microflow LC-MS in your large molecule bioanalysis efforts.
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An Introduction to High Resolution Mass Spectrometry versus Tandem Quad Mass Spectrometry for Large Molecule Bioanalysis

This presentation, presented by Ian Edwards, is designed as a primer for those new to mass spec and want to apply it to large molecule bioanalysis. It also appeals to those using triple quad MS and are exploring the benefits of HRMS for quantification of challenging samples.
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High Resolution Mass Spectrometry: Introduction to Quantitative Data Acquisition Modes on a Waters QTof for Large Molecule Bioanalysis

Hear from Mark Wrona as he discusses this next module in a series of training presentations discussing LC-MS–based quantification for large molecules using high resolution mass spectrometers.
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Case Studies in High Resolution Mass Spectrometry (HRMS) for Large Molecule Bioanalytical Quantification

In this presentation, Caitlin Dunning demonstrates the sensitivity and selectivity that can be achieved with HRMS for the quantification of peptides and proteins, speaks to some of the practical considerations to keep in mind for successful method development and more.
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High Resolution Mass Spectrometry for Quantification of Intact Monoclonal Antibodies in Plasma

In this short presentation we will go over an introduction to intact level protein quantification using LC-MS, then we will cover some of the challenges and best practices associated with this application and more.
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Developing an Automated Platform for Standardized, Large Molecule Bioanalysis

The hybrid immunoaffinity capture and surrogate peptide digest approach is an established method for LC-MS based protein quantification. However, this complex workflow is not easily implemented and requires a high level of expertise. Steven Calciano, Senior Product Manager, discusses how automation of a broadly applicable sample preparation method can address the increasing analytical demand for large molecule DMPK studies and improve laboratory efficiency.
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